Oral Liquid Washing-Drying-Capping Production Line

Xin Weisheng

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SMALL VOLUME INJECTABLES FILLING SOLUTIONS
Oral Liquid Washing-Drying-Capping Production Line
Oral Liquid Washing-Drying-Capping Production Line
OVERVIEW
The oral liquid washing-drying-filling-capping production line is composed of the QCL series vertical ultrasonic washing machine, ASMR series depyrogenation tunnel and YGZ series oral liquid filling-capping machine. Suitable for production of oral liquid containers of 2-25ml, it can complete more than 20 work procedures such as ultrasonic bathing, three-time WFI and recycled water washing, three-time compressed air flushing, exterior wall water washing and compressed air flushing, preheating, drying, sterilizing, depyrogenation, cooling, pre-fill gas purging, filling, post-fill gas purging and capping.
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FEATURES

The washing machine adopts the mechanical arms to clamp the oral liquid containers of 2-25ml;

The water-air spray nozzles adopt the reciprocating tracking insertion method for washing, featured by excellent washing effect and energy saving. It is also provided with a device that prevents the nozzle holder from shaking to enhance the accuracy of the spray nozzle's insertion into the ampoule and reduce the occurrence of nozzle breakage;

The water and air pipes are totally separable from the spray nozzles, so that cross contamination is avoided and cGMP requirements are satisfied;

The buffer block is installed before the ampoule out-feed scroll for the washing machine to protect the scroll and reduce breakage;

The depyrogenation tunnel adopts the hot air circulation heating method with even temperature and energy saving;

The depyrogenation tunnel is provided with the function of protecting against sudden power-off to ensure safe running;

The depyrogenation tunnel can be equipped with the water cooling device that does not consume air volume in the room, which can reduce the risk of unbalanced differential pressure in the room and achieve good cooling effect;

The depyrogenation tunnel can be equipped with the differential pressure automatic balancing and regulating system to eliminate the issues of deviation at the high temperature section caused by unbalanced differential pressure in the room and tunnel, and the temperature rise in the filling room and washing-drying room;

The depyrogenation tunnel is provided with the PAO inspection ports (including inspection ports for air pressure, air velocity and dust particles);

The cooling section in the tunnel is provided with the sterilization function (specially chosen by FDA)- optional;

The depyrogenation tunnel mesh belt can be equipped with the ultrasonic and CIP cleaning systems;

The depyrogenation tunnel chamber can be subject to all-round, multi-angle high pressure water washing;

The filling-sealing machine can be equipped with the ceramic pump and stainless steel pump;

The filling-capping machine is provided with the functions of no bottle no filling and no bottle no capping.

OPTIONAL ADD-ONS
According to customer requirements, it can also be equipped with the following:

Control system of brands such as Siemens, Schneider, Allen Bradley, Mitsubishi and Delta;

Online particle counting, alarm system, recording and printing systems;

ORABS, CRABS, or aseptic isolator system.

TECHNICAL PARAMETERS
Product Model
QCL100+ASMR620+YGZ16
QCL140+ASMR620+YZG24
Applicable specifications (ml) 2-25 2-20
Production capacity (pcs/min) 350-400 400-600
Number of filling heads 16 24
Number of capping heads 20 20
Gross weight (kg) 7,500
Overall dimensions (mm) 9,920 × 2,003 × 2,150
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